朱丽,张春华,徐勤.高流量鼻导管湿化吸氧在危重症患儿院内转运中的应用效果[J].上海护理,2016,16(7):
高流量鼻导管湿化吸氧在危重症患儿院内转运中的应用效果
DOI:
中文关键词:  高流量鼻导管  危重症患儿  院内转运  呼吸支持
英文关键词:High flow nasal cannula  Critically ill children  hospital transport  Respiratory support
基金项目:
作者单位E-mail
朱丽* 复旦大学附属金山医院 1109848963@qq.com 
张春华 复旦大学附属金山医院  
徐勤 复旦大学附属金山医院  
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中文摘要:
      目的 探讨高流量鼻导管湿化氧疗(HHFNC)对院内转运危重症患儿呼吸相关参数和转运不良事件影响。方法 185例需由急诊抢救室救治转运至儿科病房的危重症患儿随机分为治疗组94例和对照组91例,治疗组给予HHFNC,对照组给予经湿化瓶鼻导管或面罩给氧。比较两组患儿转运前后呼吸频率、血氧饱和度(SPO2)、动脉血氧分压(Pa O2)、动脉二氧化碳分压(PaCO2)等指标的变化情况,以及转运不良事件发生率和到达儿童病房24h内的气管插管率。结果 转运前两组患儿呼吸频率、SPO2、PaO2、PaCO2比较差异无统计学意义(P>0.05),经院内转运到达儿科病房时,治疗组上述指标与转运前比较无统计学差异,但治疗组SPO2、PaO2明显高于对照组,呼吸频率、PaCO2明显低于对照组(P<0.05)。到达儿科病房24h内治疗组15例(16.0%)患儿行气管插管,明显低于对照组有28例(30.8%),差异有统计学意义(P<0.05);两组患儿转运过程中不良事件发生率,差异无统计学意义(P>0.05)。结论 危重症患儿院内转运过程中应用HHFNC进行呼吸支持,可有效改善患儿氧合和通气功能,降低转运风险。
英文摘要:
      Objective To explore the clinical efficacy of Humidified high flow nasal cannula (HHFNC) for critically ill children who wereStransported in hospital. Methods 185 cases critically ill children who need to transport from paediatric intensive care unit to general ward were randomly divided into treatment group (94 cases) and control group (91 cases). Treatment group was given HHFNC, control group was given the wet bottle oxygen nasal cannula or mask. Changes of respiratory rate, blood oxygen saturation (SpO2), partial pressure of oxygen(PaO2), partial pressure of carbon dioxide (PaCO2) in both groups before and after transport, and adverse event rates in transport, endotracheal intubation rates during the first 24 h after the paediatric intensive care unit admission were compared. Results Compared between the two groups, no difference was found in respiratory rate, SpO2, PaO2 and PaCO2 before transport (P>0.05). The above indexes of treatment group did not significantly change between the periods of transport. And compared with control group, patients in treatment group had higher levels of SpO2, PaO2, and lower levels of respiratory rate, PaCO2 after transport (P<0.05). The endotracheal intubation rates during the first 24 h after the emergency room admission in treatment group were significantly lower than that in control group (16.0% vs 30.8%, P<0.05). There was no significant difference of adverse event rates in transport between two groups (P>0.05). Conclusion The respiratory support by HHFNC in critically ill children can improve oxygenation and ventilation function, and reduce the risk of transport.
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