| 戚倩,吴蓓雯,方琼,朱唯一.乳腺癌患者内分泌治疗期间人体成分的调查[J].上海护理,2018,18(11): |
| 乳腺癌患者内分泌治疗期间人体成分的调查 |
| Investigation of Body composition in patients in receiving endocrine therapy for breast cancer Qi Qian*, Wu Beiwen, Fang Qiong, Zhu Weiyi. * Department of Interventional Radiology, Ruijin Hospital, The Affiliated Hospital of Shanghai Jiaotong university school of medicine, Shanghai 200025,China. |
| DOI： |
| 中文关键词: 乳腺癌 内分泌治疗 人体成分 生物电阻抗 |
| 英文关键词:breast cancer endocrine therapy body composition bioelectrical impedance analysis |
| 基金项目:上海市慈善癌症中心慈善慢跑课题 |
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| 中文摘要: |
| 【摘要】 目的 观察乳腺癌患者内分泌治疗期间人体成分情况，为动态监测乳腺癌患者营养状况提供依据。方法 利用多频分节段生物电阻抗（segmental multi-frequency bioelectrical impedance analysis, SMFBIA）方法分析183例内分泌治疗期乳腺癌患者的人体成分，探讨不同内分泌治疗方案及具体药物对乳腺癌患者人体成分的影响。结果 183例内分泌治疗期乳腺癌患者中45.36%(83/183)为正常体重，50.82%（93/183）为超重或肥胖， 81.42%（149/183）患者PBF处于超标准（＞28%），49.73% (91/183)患者腰围处于超标准（＞80cm），且内分泌治疗对患者BMI、体脂肪、体脂百分比、内脏脂肪面积、腰围、上臂肌围、ECW/TBW表现明显。结论 乳腺癌患者内分泌治疗期间存在营养过剩的现象，不同内分泌治疗方案对乳腺癌患者营养状况具有一定影响，故应定期监测患者人体成分，以便全面客观评价患者营养状况，有效促进患者健康体重管理，构建获取营养相关信息的支持平台，提高诊疗效果，延长患者生存期。 |
| 英文摘要: |
| 【Abstract】 Objective To observe body composition of breast cancer patients during endocrine therapy so as to provide evidence for the dynamic monitoring of their nutritional status. Methods Segmental multi-frequency bioelectrical impedance analysis (SMFBIA)was adopted to analyze the body composition of breast cancer patients during endocrine therapy, to explore the influence of different endocrine therapy and specific drugs in patients with breast cancer . Results In 183 breast cancer patients during endocrine therapy, 45.36%(83/183) were normal weight, and 50.82%（93/183）were overweight or obese；body fat percent in 81.42% （149/183）patients for excess (> 28%)；Waist circumference in 49.73% (91/183) patients for excess（＞80cm）；Endocrine therapy for patients with BMI, body fat, body fat percentage, visceral fat area, waist circumference, upper arm muscle circumference, ECW/TBW performance significantly. Conclusions Breast cancer patients during endocrine therapy exist the phenomena of excessive nutrition, different endocrine therapy have influence on nutrition status, Body composition of breast patients should be regularly monitored in order to comprehensive and objective evaluation of patients with nutritional status, to effectively promote the patients health and weight management, for building a support platform of nutrition information, to improve the effect of diagnosis and treatment, prolong the survival. |
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