陆莉,杨柳.延迟性化疗相关恶心呕吐的干预及护理[J].上海护理,2017,17(7):
延迟性化疗相关恶心呕吐的干预及护理
DOI:
中文关键词:  CINV  化疗  恶心、呕吐、护理
英文关键词:CINV  Chemotherapy  Nausea  Vomiting  Nursing
基金项目:
作者单位E-mail
陆莉* 上海交通大学医学院附属瑞金医院 ll20745@rjh.com.cn 
杨柳 上海交通大学医学院附属瑞金医院 ll20745@rjh.com.cn 
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中文摘要:
      目的 探讨肿瘤患者延迟性相关恶心呕吐干预举措的效果。方法 选取2015年1月至2015年12月在上海交通大学医学院附属瑞金医院肿瘤科收治的接受含顺铂(>70mg/m2)联合化疗方案的实体肿瘤患者45例。评估入组患者在使用阿瑞匹坦后恶心呕吐发生率的差异。同时根据相关量表,评估干预处理后,患者焦虑抑郁的改善情况。结果 阿瑞匹坦联合相关护理干预措施后III度以上恶心呕吐发生率较干预前明显降低,且焦虑抑郁情绪较前明显好转,差异具有显著统计学差异(P<0.001)。结论 在止吐药物合理组合应用的基础上,相应的护理干预举措能进一步减少化疗相关恶心呕吐的发生,对于减少患者痛苦,促进护患关系的和谐发展起到了重要的作用。
英文摘要:
      Objective To investigate the effect of intervention measures on delayed chemotherapy-induced nausea and vomiting in cancer patients. Methods A total of 45 patients with solid tumor treated with cisplatin (>70mg/m2) combined with chemotherapy were selected from Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine from January 2015 to December 2015. Evaluate the difference in the incidence of nausea and vomiting after using aprepitant. Furthermore, evaluate the improvement of anxiety and depression after intervention measures. Results The incidence of severe nausea and vomiting were decreased after aprepitant combined nursing intervention compared with before intervention. Anxiety and depression were significantly better than before. Conclusion Based on the application of reasonable combination of antiemetic drugs, the nursing intervention measures could reduce the incidence of chemotherapy-induced nausea and vomiting. It plays an important role in reducing the pain of patients and promoting the harmonious relationship between nurse and patient.
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