| 李娜,钟云萍,孙圣荣.渐进式肌肉放松训练对乳腺癌高致吐方案化疗所致恶心呕吐的效果观察[J].上海护理,2019,19(1): |
| 渐进式肌肉放松训练对乳腺癌高致吐方案化疗所致恶心呕吐的效果观察 |
| Efficacy of progressive muscle relaxation training in preventing chemotherapy-induced nausea and vomiting in patients with breast cancer |
| DOI： |
| 中文关键词: 渐进式肌肉放松训练 乳腺癌 化疗 恶心呕吐 |
| 英文关键词:Progressive muscle relaxation training breast cancer chemotherapy nausea and vomiting. |
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| 中文摘要: |
| 目的 探讨渐进式肌肉放松训练对乳腺癌高致吐方案化疗所致恶心呕吐(CINV)的治疗效果。方法 收集我院2017年1月-2017年6月行表阿霉素联合环磷酰胺(EC)方案化疗的乳腺癌患者68例,按照随机数字表法分为观察组和对照组,每组各34例。对照组给予托烷司琼注射液、地塞米松治疗；观察组在此基础上进行渐进式肌肉放松训练,比较两组对预防CINV的临床疗效。结果 急性期两组恶心、呕吐发生率、恶心缓解率及呕吐频次比较,差异均无统计学意义(P>0.05)；延迟期两组恶心发生率比较,差异无统计学意义(P>0.05),观察组呕吐发生率、呕吐频次明显低于对照组,恶心缓解率明显高于对照组,差异有统计学意义(P<0.05)。结论 渐进式肌肉放松训练能显著降低乳腺癌高致吐方案化疗延迟期呕吐发生率、呕吐频次和恶心程度,简便易行,可用于临床防治乳腺癌高致吐方案化疗所致CINV。 |
| 英文摘要: |
| To observe the effect of progressive muscle relaxation training on nausea and vomiting caused by emetic programme chemotherapy in breast cancer.Methods A total of 68 patients in our hospital from January 2017-June 2017 who accept EC programme chemotherapy were randomly divided into observation group and control group,34 cases in each group.The control group was treated with tropisetron injection and dexamethasone;the observation group was given progressive muscle relaxation training on this basis,and the clinical efficacy of the two groups in preventing chemotherapy-induced nausea and vomiting was compared.Results There were no significant difference in the incidence of nausea and vomiting,the severity of nausea ,the frequency of vomiting between the two groups in acute phase (p>0.05);There was no significant difference in the incidence of nausea between the two groups in delayed phase (p>0.05);The incidence of vomiting and frequency of vomiting in the observation group were significantly lower than that in the control group,and the rate of nausea relief was higher than that in the control group in delayed phase,the difference was statistically significant(p<0.05).Conclusion Progressive muscle relaxation training can significantly reduce vomiting frequency, incidences and severity of nausea in delayed phase, is simple and convenient,can be used for the clinical prevention and treatment of CINV caused by emetic programme chemotherapy in breast cancer. |
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