| 孙真真.高血压脑出血术后昏迷患者ICU获得性衰弱发生现状及危险因素[J].上海护理,2025,25(2): |
| 高血压脑出血术后昏迷患者ICU获得性衰弱发生现状及危险因素 |
| Current status and risk factors of ICU acquired frailty in coma patients after hypertensive intracerebral hemorrhageSun Zhenzhen1,Ma Rui1,Sun Sijia2 |
| DOI： |
| 中文关键词: 高血压脑出血 昏迷 重症监护病房获得性衰弱 现状 危险因素 |
| 英文关键词:hypertensive cerebral hemorrhage coma acquired weakness in intensive care unit current situation risk factors |
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| 中文摘要: |
| 目的：探讨高血压脑出血术后昏迷患者ICU获得性衰弱(ICU-AW)发生现状,并分析其危险因素,为制定有效措施降低ICU-AW发生率提供依据。方法：根据便利抽样法选取2021年2月至2023年4月在ICU接受治疗的107例高血压脑出血术后昏迷患者,记录ICU-AW发生情况,采用多因素Logistic回归分析高血压脑出血术后昏迷患者发生ICU-AW的危险因素。结果：单因素分析,发生ICU-AW组与未发生ICU-AW组比较,有无糖尿病史、合并脓毒症、合并多器官功能衰竭差异具有统计学意义(P＜0.05),机械通气时间、ICU入住时间差异具有统计学意义(P＜0.05),是否应用糖皮质激素、神经肌肉阻滞剂以及镇静镇痛药物使用次数比较差异有统计学意义(P＜0.05)；多因素Logistic回归分析,有糖尿病史、合并脓毒症、合并多器官功能衰竭、机械通气时间≥7d、ICU入住时间≥7d、应用糖皮质激素、应用神经肌肉阻滞剂、镇静镇痛药物使用次数≥4次是高血压脑出血术后昏迷患者发生ICU-AW的危险因素(OR＞1,P＜0.05)。结论：有糖尿病史、合并脓毒症、合并多器官功能衰竭、机械通气时间≥7d、ICU入住时间≥7d、应用糖皮质激素、应用神经肌肉阻滞剂、镇静镇痛药物使用次数≥4次均是高血压脑出血术后昏迷患者发生ICU-AW的危险因素,临床应针对危险因素制定对应方案,以降低ICU-A发生率。 |
| 英文摘要: |
| Objective: To explore the status of ICU acquired frailty (ICU-AW) in coma patients after hypertensive cerebral hemorrhage, and analyze the risk factors to provide a basis for developing effective measures to reduce the incidence of ICU-AW. Methods: 107 coma patients from February 2021 to April 2023 were selected to record the occurrence of ICU-AW and analyze the risk factors of ICU-AW by multivariate Logistic regression. Results: Univariate analysis, ICU-AW versus no ICU-AW, Significant difference between history of diabetes, sepsis, and multiple organ failure (P <0.05), The difference between mechanical ventilation time and ICU stay time was statistically significant (P <0.05), Compared with the use of glucocorticoids, neuromuscular blockers and sedative and analgesic drugs (P <0.05); Multivariate Logistic regression analysis, A history of diabetes, sepsis, multiple organ failure, time of mechanical ventilation 7d, ICU admission time 7d, application of glucocorticoids, application of neuromuscular blockers, and use of sedative and analgesic drugs were four risk factors for ICU-AW in coma patients after hypertensive intracerebral hemorrhage (OR> 1, P<0.05). Conclusion: A history of diabetes, sepsis, multiple organ failure, mechanical ventilation, 7d, ICU stay 7d, application of glucocorticoids, neuromuscular blockers, sedative analgesic use of 4 times are the risk factors of ICU-AW in coma patients after hypertensive cerebral hemorrhage, clinical should be a corresponding plan for the risk factors to reduce the incidence of ICU-A. |
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