| 袁勇勇,沈小雁,徐莲英.窄谱中波紫外线治疗早期蕈样肉芽肿的疗效及护理[J].上海护理,2015,15(8): |
| 窄谱中波紫外线治疗早期蕈样肉芽肿的疗效及护理 |
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| 投稿时间：2013-03-19 修订日期：2013-03-19 |
| DOI： |
| 中文关键词: 早期蕈样肉芽肿 窄谱中波紫外线 疗效 护理 |
| 英文关键词:early-stage mycosis fungoides NB-UVB efficacy nursing |
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| 中文摘要: |
| 【】 目的 总结窄谱中波紫外线(NB-UVB)治疗早期蕈样肉芽肿(mycosis fungoides,MF)的疗效及护理措施。方法 收集本科2008年1月—2012年12月收治的37例经临床和病理证实为早期MF(IA-IB)并接受NB-UVB规范治疗的患者临床资料。治疗过程中严格执行紫外线防护工作,加强护理及健康指导。结果 治疗结束后,37例早期MF中,IA 17例,IB 20例,完全缓解(CR)31例(83.78%),部分缓解(PR)5例(13.51%),好转1例(2.7%),无缓解0例,有效率97.3%(CR+PR)。平均照射次数(24.78 ? 8.01)次,平均累计剂量(35.34 ? 22.67)J/CM2。主要不良反应为红斑、瘙痒及色素沉着,患者均能耐受。结论 认为NB-UVB治疗早期蕈样肉芽肿安全有效,注重治疗过程中的护理及健康教育可以保证治疗效果。 |
| 英文摘要: |
| 【】 Objective： To summarize the efficacy and nursing interventions of Narrowband UVB(NB-UVB) in early-stage Mycosis Fungoides(MF). Methods: Retrospectively reviewed 37 patients who were clinically and pathologically diagnosed as early-stage MF in our department from January 2008 to December 2012. The patients were treated with NB-UVB according to the routine procedures and the nursing and health guidance. Results: In all 37 patients, 17 in stage IA and 20 in stage IB. 31 patients had a complete remission (83.78%), 5 patients had a partial response (13.51%), 1 patients had improvement(2.7%). The total response rate was 97.3%. The average radiation times was (24.78 ± 8.01),and mean accumulated radiation dose 35.34 J/CM2.The main side effects were erythema, pruritus and hyperpigmentation, which were all tolerable. Conclusion: NB-UVB was a safe and effective therapy for patients with early-stage MF. Appropriate nursing and health education could be beneficial to guarantee and increase the efficacy, and further prevent the recurrence of the disease. |
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