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梁家青,侯黎莉▲.生活方式及膳食行为因素与口腔癌关系的Meta分析[J].上海护理,2024,24(11):

生活方式及膳食行为因素与口腔癌关系的Meta分析

Meta-analysis of the relationship between lifestyle and dietary behavior factors and oral cancer

投稿时间：2023-09-13 修订日期：2024-11-01

DOI：

英文关键词:Oral cancer Diet Lifestyle Meta analysis

基金项目:]:长三角科技创新共同体项目(编号21002411300)

作者	单位	E-mail
梁家青	成都中医药大学护理学院	1900760123@qq.com
侯黎莉▲^*	上海交通大学医学院附属第九人民医院	pisces_liz@163.com

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中文摘要:

目的探讨个人生活方式及膳食行为与口腔癌发病风险之间的关系，为制定口腔癌防治措施提供依据。方法计算机检索中国知网、维普、万方、Embase、PubMed和Cochrane Library数据库，收集建库至2023年10月发表的关于口腔癌危险因素的病例对照研究文献，并应用RevMan 5.3软件对纳入研究进行Meta分析。结果共纳入16篇文献，包含5982例病例。Meta分析结果显示，口腔癌的保护因素有食用鱼类[OR=0.55,95%CI(0.51,0.60),P<0.001]、海鲜[OR=0.49,95%CI(0.45,0.53),P<0.001]、奶类及奶制品[OR=0.60,95%CI(0.56,0.65),P<0.001]、蛋类[OR=0.71,95%CI(0.65,0.78),P<0.001]、绿叶蔬菜[OR=0.28,95%CI(0.25,0.32),P<0.001]、非绿叶蔬菜[OR=0.34,95%CI(0.31,0.38),P<0.001]、水果[OR=0.32,95%CI(0.29,0.35),P<0.001]、补充维生素[OR=0.40,95%CI(0.29,0.55),P<0.001]以及补充保健品[OR=0.40,95%CI(0.30,0.53),P<0.001]；口腔癌的危险因素有食用腌制品[OR=1.15,95%CI(1.05,1.25),P=0.002]、饮酒[OR=2.05,95%CI(1.85,2.28),P<0.001]以及吸烟[OR=1.87,95%CI(1.59,2.20),P<0.001]。结论个人生活方式及膳食行为因素和口腔癌发病关系密切，常食鱼类、海鲜、奶类及奶制品、蛋类、蔬菜、水果以及补充维生素和保健品可降低口腔癌的患病风险；而常食腌制食品、饮酒、吸烟会增加口腔癌的患病风险，应进行针对性的重点关注和防控。

英文摘要:

Objective To investigate the relationship between individual lifestyle and dietary behaviors and the risk of oral cancer,and to provide evidence for the development of oral cancer prevention and treatment measures. Methods The CNKI,VIP,Wan Fang,Embase,PubMed,and Cochrane Library databases were searched on computer to collect case-control study literature on the risk factors of oral cancer which were published from the establishment of the database to October 2023, and the RevMan 5.3 software was applied to perform Meta-analysis of the included studies. Results A total of 16 literatures were included, containing 5982 cases.The results of Meta-analysis showed that the protective factors of oral cancer were the consumption of fish[OR=0.55,95%CI(0.51,0.60),P<0.001],seafood[OR=0.49,95%CI(0.45,0.53),P<0.001],milk and dairy products[OR=0.60,95%CI(0.56,0.65),P<0.001],eggs[OR=0.71,95%CI(0.65,0.78),P<0.001],green leafy vegetable[OR=0.28,95%CI(0.25,0.32),P<0.001],non green leafy vegetable[OR=0.34,95%CI(0.31,0.38),P<0.001],fruits[OR=0.32,95%CI(0.29,0.35),P<0.001],vitamin supplement[OR=0.40,95%CI(0.29,0.55),P<0.001] and health supplement[OR=0.40,95%CI(0.30,0.53),P<0.001];The risk factors of oral cancer were consumption of pickled products[OR=1.15,95%CI(1.05,1.25),P=0.002],alcohol consumption[OR=2.05,95%CI(1.85,2.28),P<0.001],and smoking[OR=1.87,95%CI(1.59,2.20),P<0.001].Conclusion Individual lifestyle and dietary behaviors factors were closely related to the development of oral cancer.Regular consumption of fish,seafood,milk and dairy products,eggs,vegetables,fruits,and vitamin and health supplements might reduce the risk of oral cancer.And frequent consumption of pickled products,alcohol consumption and smoking might increase the risk of oral cancer,which should be targeted to focus on the prevention and control of oral cancer.

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