| 陈澜,葛燕萍,沈玉芳,孙亚慧,徐健,白斌,马雯琦,张兵.合募配穴法艾灸治疗改道性结肠炎患者腹泻的临床疗效观察[J].上海护理,2025,25(11): |
| 合募配穴法艾灸治疗改道性结肠炎患者腹泻的临床疗效观察 |
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| 投稿时间：2024-08-30 修订日期：2025-11-06 |
| DOI： |
| 中文关键词: 合募配穴 艾灸 改道性结肠炎 炎症因子 腹泻 中医证候 |
| 英文关键词:combination of he-mu acupoints Moxibustion Diversion colitis Inflammatory factors Diarrhea TCM syndromes |
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| 中文摘要: |
| 目的 观察合募配穴法艾灸对改道性结肠炎患者的治疗效果，以期为临床实践提供依据。方法 选取2022年10月1日至2024年6月1日在上海市宝山区中西医结合医院治疗的改道性结肠炎患者70例为研究对象。采用随机数字表法将患者分为观察组与对照组，各35例。对照组患者接受基础治疗（禁食、抑酸护胃、补充电解质、调节肠道菌群、止泻等对症处理），观察组患者在对照组的基础上辅以艾灸双侧天枢穴、上巨虚穴。收集干预前后1周患者血清炎症因子（WBC、中性粒细胞、C反应蛋白、白细胞介素-6、白细胞介素-6、肿瘤坏死因子-α、白细胞介素-1β）、腹泻严重程度评分及中医症候疗效结果。结果 观察组和对照组患者血清炎症因子水平均较干预前降低，且观察组均低于对照组（P<0.05）。干预后两组腹泻严重程度评分较干预前均明显下降，观察组较对照组更低（P<0.05）。观察组中医症候治疗总有效率为97.14%，明显高于对照组的85.71%（χ2=7.819,P=0.04）。结论 合募配穴法艾灸治疗能显著改道性结肠炎患者炎症因子水平，缓解患者腹泻症状，提高临床治疗有效率。 |
| 英文摘要: |
| Abstract: Objective To observe the effect of moxibustion on the levels of inflammatory factors, diarrhea severity score and TCM syndrome score in patients with diversion colitis and its clinical efficacy. Methods To choose October 1, 2021 - on October 1, 2023 in XX treatment diversion colitis patient 70 examples, they were divided into observation group and control group with 35 cases in each group using the random number table method . Control group based therapy （fasting, protecting stomach acid suppression, electrolytes, regulating intestinal flora, antidiarrheal cure, etc）, the observation group based on the control group with moxibustion bilateral days on the pivot point and giant. One week before and after treatment, the serum inflammatory factors （WBC, Neutrophil, C-reactive Protein, Interleukin-6,Interleukin-7, Tumor Necrosis Factor-alpha, Interleukin-1 beta）, diarrhea severity score and TCM syndrome efficacy results were collected. Results The levels of WBC, NEUT, CRP, IL-6, IL-7, TNF α, and IL-1 β in the observation group and control group decreased compared to before treatment, and the observation group was lower than the control group （P<0.05）. In the two groups after treatment of diarrhea severity score before treatment were significantly lower,and the observation group was lower than the control group （P<0.05）.The effective rate of traditional Chinese medicine syndrome treatment in the observation group（97.14%） is significantly higher than that in the control group（85.71%） （chi-square = 7.819, P = 0.04）. Conclusion Moxibustion at He-mu acupoints combined with moxibustion can significantly reduce the levels of inflammatory factors WBC, NEUT, CRP, il6, il7, TNFα and il1β in patients with diversion colitis, relieve the symptoms of diarrhea, and improve the clinical effective rate. |
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