| 刘桂林,麻晓君,张荣,方丹,袁晓丹,顾莎莎.运动干预对2型糖尿病患者颈动脉内膜中层厚度影响的Meta分析[J].上海护理,2026,26(1): |
| 运动干预对2型糖尿病患者颈动脉内膜中层厚度影响的Meta分析 |
| Meta-Analysis on the Effect of Exercise Interventions on Carotid Intima-Media Thickness in Patients with Type 2 Diabetes Mellitus |
| 投稿时间：2025-04-01 修订日期：2026-01-08 |
| DOI： |
| 中文关键词: 运动干预 运动形式 运动强度 2型糖尿病 颈动脉内膜中层厚度 Meta分析 |
| 英文关键词:Exercise interventions Movement forms Exercise intensity Diabetes mellitus, type 2 Carotid intima-media thickness Meta-analysis |
| 基金项目:2023年度预防医学课题面上项目（Ym2023048）；湖南省自然科学基金区域联合项目（2022JJ50027）；2025年江苏省研究生实践创新计划（SJCX25_1104） |
|
| 摘要点击次数: 800 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的 评价不同形式不同强度的运动干预对2型糖尿病（T2DM）患者颈动脉内膜中层厚度（CIMT）的影响。
方法 检索PubMed、Cochrane Library、Web of Science、中国知网、万方数据知识服务平台、维普资讯中文期刊服务平台、中国生物医学文献服务系统7个中英文数据库中关于运动干预对T2DM患者CIMT影响的随机对照试验，检索时间为从建库至2024年1月10日。文献筛选、质量评价和数据提取由2名研究者独立完成。使用RevMan 5.4和Stata 16软件进行Meta分析。通过亚组分析和敏感性分析寻找异质性来源。
结果 共纳入7篇文献，680例受试者。Meta分析结果显示，接受运动干预的T2DM患者较对照组CIMT显著降低［MD=-0.06，95% CI (-0.09，-0.04)，P<0.05］。亚组分析结果显示，与有氧联合抗阻运动干预相比，有氧运动更显著地降低CIMT（P<0.05）。在不同有氧运动强度干预效果上，中等强度持续运动优于高强度间歇运动。Egger’s检验结果为t=0.58，P>0.05，未表现出显著的发表偏倚。
结论 运动干预可使T2DM患者CIMT显著减低，其中有氧运动尤其中等强度持续运动在改善CIMT方面的效果更优。 |
| 英文摘要: |
| Objective To evaluate the effects of different forms and intensity of exercise interventions on carotid intima-media thickness (CIMT) in patients with type 2 diabetes mellitus (T2DM).
Methods Seven Chinese and English databases, including PubMed, Cochrane Library, Web of Science, CNKI, Wanfang Data, VIP, and SinoMed were searched for randomized controlled trials assessing the effects of exercise interventions on CIMT in patients with T2DM. The search period ranged from database establishment to January 10th, 2024. Two researchers independently carried out literature screening, quality evaluation and data extraction. Meta-analysis was conducted using RevMan 5.4 and Stata 16 software. Subgroup analysis and sensitivity analysis were employed to identify potential sources of heterogeneity.
Results Seven studies involving a total of 680 subjects were included in this meta-analysis. The results demonstrated that patients with T2DM receiving exercise intervention in the experimental group exhibited a significant reduction in CIMT compared to those in the control group [MD=-0.06, 95% CI (-0.09, -0.04), P<0.05]. Subgroup analysis revealed that compared with aerobic combined resistance exercise intervention, aerobic exercise significantly reduced CIMT (P<0.05). In terms of the effects of different aerobic exercise intensity interventions, moderate-intensity continuous exercises were better than high-intensity interval exercises. Egger’s test result did not show any significant publication bias (t=0.58, P>0.05).
Conclusion Exercise interventions significantly reduce CIMT among patients with T2DM, among which aerobic exercise, especially moderate-intensity continuous exercise, has a more significant effect on improving CIMT. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|