| 吴冠虹,郑翠红.不同体质指数对高热患者药物降温效果的影响[J].上海护理,2018,18(8): |
| 不同体质指数对高热患者药物降温效果的影响 |
| Influence of Body Mass Index on the Process of Therapeutic Hypothermia Using Pharmaceutical in Febrile Inpatients |
| DOI： |
| 中文关键词: 体质指数 降温治疗 药物 高热患者 |
| 英文关键词:body mass index therapeutic hypothermia pharmaceutical febrile patient. |
| 基金项目:福建省科技厅重点项目 |
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| 中文摘要: |
| 【】目的：探讨不同体质指数对高热患者药物降温效果的影响。方法：选取福州某三甲医院呼吸内科2016年4月至10月采用药物降温的发热病人(T≥38.5℃)110例,根据体质指数不同分为偏瘦组、正常组和超胖组,评价不同体质指数对高热患者药物降温效果的影响。结果：共110例患者纳入研究,服药后30分钟内各组患者降温速度存在显著差异(P＜0.05),以正常组降温速度最快；30分钟至60分钟各组降温速度无显著差异(P＞0.05)。降温处理后30min各组的降温有效率分别为13.6%、38.7%、15.4%；60min分钟各组的有效率为54.5%、93.5%、100%,均存在显著差异(P＜0.05)。各组体温降至38℃所需的时间均值分别为82.27、71.93、67.69分钟,无显著差异(P＞0.05)。结论 ：不同体温指数对高热患者药物降温的速度和疗效存在影响,服药后30分钟以正常体质指数组患者降温速度最快。药物降温过程中应关注到患者的体质指数情况,对异常体质指数患者要更为密切关注药物的降温效果。 |
| 英文摘要: |
| Objectives: The aim of this study is to investigate whether obesity classification by body mass index has impact on the process of therapeutic hypothermia. Methods: Cohort study was employed. The data were collected from febrile inpatients who were admitted to Respiratory Department from April to October in 2016. Patients whose temperature ≥38.5℃and treated with pharmaceutical were included. Temperature at each group were measured before and after application of drugs every 30 minutes until it was under 38℃. Results: 110 patients were enrolled in the study. Cooling rate at 30 minutes in each group was significantly different (P <0.05), and in the normal group the rate of cooling was the fastest. There was no significant difference in the cooling rate between 30 and 60 minutes (P> 0.05). At 30minutes the effective rates.were respectively 13.6%, 38.7% and 15.4%. At 60minutes the effective rate was 54.5%, 93.5% and 100% in each group (P <0.05). The mean time of temperature drop to 38 ℃ were 82.27, 71.93 and 67.69 minutes. There was no significant difference (P> 0.05).Conclusion: It is concluded that BMI had an impact on the outcome of TH at the initial stage when conducting therapeutic hypothermia to a fever patient. Abnormal BMI patients require more attention. Further studies about the mechanisms are needed to support this finding.
Keywords: body mass index; therapeutic hypothermia; pharmaceutical; febrile patient. |
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