| 魏宇,宋雅丽,袁丽莎,尹迪,王欢,张云凤.活血化瘀中药外用对维持性血液透析患者动静脉内瘘功能影响的Meta分析[J].上海护理,2020,20(11): |
| 活血化瘀中药外用对维持性血液透析患者动静脉内瘘功能影响的Meta分析 |
| Effect of external application of HuoXueHuaYu Chinese herbs on arteriovenous fistula function in maintenance hemodialysis patients：a Meta-analysis |
| DOI： |
| 中文关键词: 活血化瘀 中药 维护 动静脉内瘘 Meta分析 |
| 英文关键词:HuoXueHuaYu traditional Chinese medicine maintenance Arteriovenous fistula Meta-analysis |
| 基金项目:北京中医药大学青年教师项目 |
|
| 摘要点击次数: 1853 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的 系统评价活血化瘀中药外用对维持性血液透析患者动静脉内瘘(Arteriovenous Fistula,AVF)功能的影响。方法 计算机检索CNKI、万方数据知识服务平台、维普中文科技期刊数据库、中国生物医学文献数据库、PubMed、Cochrane Library、EMBase、Web of Science数据库,由两名研究者单独筛选文献、提取资料。采用RevMan 5.3软件进行Meta分析,采用Cochrane偏倚风险评估工具对纳入文献进行质量评价。结果 共纳入26篇随机对照试验,共2039例MHD患者。Meta分析结果显示,观察组皮下血肿治疗有效率〔相对危险度(RR)=1.25,95%CI(1.19,1.32),P＜0.00001〕、血管硬结改善率〔相对危险度(RR)=1.44,95%CI(1.18,1.75),P=0.0003〕、血管杂音增强率〔相对危险度(RR)=1.55,95%CI(1.31,1.83),P＜0.00001〕高于对照组,差异有统计学意义。观察组血管硬结发生率〔相对危险度(RR)=0.11,95%CI(0.06,0.22),P＜0.00001〕、血管狭窄发生率〔相对危险度(RR)=0.32,95%CI(0.20,0.49),P＜0.00001〕、内瘘闭塞发生率〔相对危险度(RR)=0.15,95%CI(0.07,0.33),P＜0.00001〕、假性假性动脉瘤发生率〔相对危险度(RR)=0.51,95%CI(0.35,0.75),P=0.0006〕均低于对照组,差异有统计学意义。结论 基于目前证据,对于AVF的维护,联用活血化瘀中药能更好地治疗内瘘穿刺后皮下血肿、软化血管硬结、增强血管杂音,且能预防血管硬结、血管狭窄、内瘘闭塞、假性假性动脉瘤并发症的发生。 |
| 英文摘要: |
| Objective To evaluate the effects of external application of HuoXueHuaYu traditional Chinese medicine on Arteriovenous Fistula (AVF) function in patients with maintenance hemodialysis (MHD). Methods We searched CNKI, Wanfang Data, VIP, CBM, PubMed, Cochrane Library, Embase and Web of Science database for studies evaluating the efficacy of papaya external application to protect Autogenous Arteriovenous Fistula (AVF) in maintenance hemodialysis (MHD) patients. Studies screening and data extraction were performed by two researchers separately. Meta-analysis was conducted with RevMan 5.3. The quality of the included literature was evaluated using the Cochrane bias risk assessment tool. Results A total of 26 randomized controlled trials involving a total of 2039 patients with MHD were included. Meta-analysis showed that the observation group had a subcutaneous hematoma treatment efficiency (relative risk (RR) = 1.25, 95% CI (1.19, 1.32), P < 0.00001], and vascular induration improvement rate (relative risk (RR) = 1.44, 95% CI (1.18, 1.75), P=0.0003], vascular noise enhancement rate [relative risk (RR) = 1.55, 95% CI (1.31, 1.83), P <0.00001] was higher than the control group, the difference was statistically significant significance. The incidence of vascular induration [relative risk (RR) = 0.11, 95% CI (0.06, 0.22), P < 0.00001], incidence of vascular stenosis [relative risk (RR) = 0.32, 95% CI (0.20, 0.49), P<0.00001], incidence of internal hemorrhoid occlusion [relative risk (RR) = 0.15, 95% CI (0.07, 0.33), P < 0.00001], and aneurysm incidence [relative risk (RR) = 0.51 95% CI (0.35, 0.75), P=0.0006) in the observation group were lower than the control group, and the difference was statistically significant. Conclusion Based on the current evidence, for the maintenance of AVF, combined with HuoXueHuaYu Chinese medicine can better treat subcutaneous hematoma after internal hemorrhoid puncture, soften vascular induration, enhance vascular murmur, and prevent the occurrence of complications that vascular induration, vascular stenosis, internal stenosis, arteries and tumor. |
| 查看/发表评论 下载PDF阅读器 全文HTML |
| 关闭 |
|
|
|
